The Vitiligo & Pigmentation Institute of Southern California
With Decades of Experience Treating Patients of All Ethnicities and Skin Types
Check out Clinical Trials Currently Open for Enrollment
We have clinical trials open for acne and sunscreen use. If you qualify these research options are at no cost to you.
Pearl E. Grimes MD, FAAD
Treats a Wide Variety of Common Skin Disorders & Provides a Full Range of Dermatologic Care
Innovative approaches for the Evaluation and Treatment of Vitiligo
Including Excimer Laser, Narrow Band UVB Phototherapy Laser, Targeted Phototherapy and Surgical Grafting
Meet Pearl E. Grimes MD, FAAD

Dermatologist Los Angeles

Pearl E. Grimes MD, FAAD is the Director of the Vitiligo & Pigmentation Institute of Southern California and is highly renowned international authority on vitiligo and pigmentary disorders. Dr. Grimes is currently serving as a Clinical Professor of Dermatology at UCLA. Her all-encompassing and dedicated approach to treating these disorders has attracted patients from various regions of the world for her expertise. She is both a clinician, researcher, and orator, lecturing globally on pigmentation disorders. She has also shared her expertise on cosmetic procedures such as fillers, chemical peeling, and microdermabrasion.

Dr. Grimes has received recognition within the field by being awarded the prestigious Dermatology Foundation “Practitioner of the Year” Award in 2011 and the Women’s Dermatological Society “Mentor of the Year’ award. She was placed on LA Magazine’s Super Doctors ® list for five consecutive years and on the “Best Doctors of America” list for the previous 12 years. Dr. Grimes was named as one of Hollywood’s Top Doctors by her peers for 2014 and 2015 in The Hollywood Reporter. Dr. Grimes is known for her ongoing research and is actively involved in performing Clinical Trials


Dr. Grimes provides therapy for vitiligo with the goal of recovering natural skin color by restoring melanocytes on the skin.


Melasma can be treated with multiple therapies offered by Dr. Grimes, these include microdermabrasion, Fraxel laser, IPL, chemical peels, salicylic acid, and more.


Patients experiencing alopecia or hair loss are referred to Dr. Grimes’ medical facility, which is an advanced center specialized in treating dermatologic conditions.


Dr. Grimes uses multiple approaches for the treatment of acne to slow its severity and prevent additional scarring.


BOTOX is a safe and FDA-approved treatment that can reverse the signs of aging while treating frown lines between the brows.

Chemical Peels
Chemical Peels

We provide chemical peels on an outpatient basis and will result in smooth, softer skin with improvements in scarring and fine wrinkles.

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Katalaya Skin Care

Katalaya™ Skin Care line is exclusively formulated for all skin types with carefully selected ingredients that target particular concerns. It has been successfully used to improve even the most difficult challenges.

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Juvéderm®, Perlane®, Restylane® are smooth consistency gels made of hyaluronic acid—a naturally occurring substance in your skin that helps to add volume and hydration.

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Thermage is clinically proven to provide benefits to skin in the form of a smoother, younger looking appearance. The treatment provides and effective method of addressing fine lines and wrinkles.

Our Mission

The Institute, a professional, independent medical organization, is committed to:
  • Leadership and excellence in delivering quality healthcare services
  • Expanding advances in diagnostic, etiology and treatment of pigmentary disorders through medical research
  • Educating and training healthcare professionals
  • Striving to improve and address the dermatologic needs of our community
Quality patient care is our priority. Providing excellent clinical and service quality, offering compassionate care, and conducting innovative research and medical education are essential to our mission.
In pursuing this mission, the Institute recognizes that adherence to ethical standards and compliance with applicable laws is critical to the practice’s ability to continue its collaboration with health care professionals, patients and the community.

Katalaya Skin Care


The Katalaya skin care line is exclusively formulated for all skin types with carefully selected ingredients that target particular concerns. It has been successfully used to improve even the most difficult challenges, for example, acne, melasma, post inflammatory hyper pigmentation, uneven skin tone, dullness, textural changes and the appearance of aging skin.

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